Alpine Immune Sciences Inc (ALPN) Ownership

6.74 ↑0.24 (3.69%)
As of Market Close on December 5th, 2022.

Institutional Ownership

Orbimed Advisors, LLC is the biggest individual institutional holder of Alpine Immune Sciences Inc (ALPN), owning a total of 4.1 million shares. Combined, the top 20 institutional holders of ALPN own 42.57% of the company with a total of 19.5 million shares.

In the latest ownership report on September 30th 2022, the top 20 institutional holders increased their combined ownership of ALPN by 6.5 million shares. 9 institutions bought 6,832,533 total additional shares and increased their ownership by an average of 100.17%. However 1 institutions sold 323,691 total shares and decreased their ownership by an average of 55.98%.

Overall this is a positive sign as the number of shares owned by the top 20 institutional holders of Alpine Immune Sciences increased by a net total of 6,508,842 in the latest quarter.

Institution Ownership Chart

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Latest Institutional Ownership Changes

OwnerPercent OwnedPercent ChangeShares OwnedShare ChangeDate Reported
Great Point Partners LLC7.511%540.015%3,448,5212,909,7022022-09-30
Paradigm Biocapital Advisors LP4.824%167.874%2,214,7221,387,9432022-09-30
Omega Fund Management LLC4.421%0.000%2,029,58002022-09-30
COMMODORE CAPITAL LP2.886%0.000%1,325,0001,325,0002022-09-30
Artal Group S A2.599%101.175%1,193,030600,0002022-09-30
Vanguard Group Inc2.446%78.287%1,122,800493,0272022-09-30
Avidity Partners Management LP2.175%0.004%998,600352022-09-30
State Street Corporation0.608%4.066%278,98210,9002022-09-30
TCG Crossover Management, LLC0.555%-55.977%254,569-323,6912022-09-30
Monashee Investment Management LLC0.218%0.000%100,000100,0002022-09-30
Bank of New York Mellon Corp0.140%10.121%64,4805,9262022-09-30
Dimensional Fund Advisors, Inc.0.112%0.000%51,37002022-09-30

Top Institutions

OwnerPercent OwnedPercent ChangeShares OwnedShare ChangeDate Reported
Orbimed Advisors, LLC8.890%0.000%4,081,59202022-06-30
Great Point Partners LLC7.511%540.015%3,448,5212,909,7022022-09-30
Paradigm Biocapital Advisors LP4.824%167.874%2,214,7221,387,9432022-09-30
Omega Fund Management LLC4.421%0.000%2,029,58002022-09-30
COMMODORE CAPITAL LP2.886%0.000%1,325,0001,325,0002022-09-30
Bvf Inc2.778%-19.771%1,275,240-314,2552022-06-30
Artal Group S A2.599%101.175%1,193,030600,0002022-09-30
Vanguard Group Inc2.446%78.287%1,122,800493,0272022-09-30
Avidity Partners Management LP2.175%0.004%998,600352022-09-30
Renaissance Technologies Corp0.866%2.927%397,39411,3002022-06-30
State Street Corporation0.608%4.066%278,98210,9002022-09-30
TCG Crossover Management, LLC0.555%-55.977%254,569-323,6912022-09-30
Geode Capital Management, LLC0.540%15.262%247,99232,8362022-06-30
Allspring Global Investments Holdings, LLC0.298%711.274%136,797119,9352022-06-30
Northern Trust Corp0.274%23.662%125,77424,0662022-06-30
Two Sigma Advisers, LLC0.221%-11.036%101,575-12,6002022-06-30
Monashee Investment Management LLC0.218%0.000%100,000100,0002022-09-30
Bridgeway Capital Management, LLC0.208%-34.338%95,611-50,0002022-06-30
Bank of New York Mellon Corp0.140%10.121%64,4805,9262022-09-30
Dimensional Fund Advisors, Inc.0.112%0.000%51,37002022-09-30

Mutual Fund Ownership

Vanguard Total Stock Mkt Idx Inv is the biggest individual fund holder of Alpine Immune Sciences Inc (ALPN), owning a total of 852 thousand shares. Combined, the top 20 mutual fund holders of ALPN own 6.91% of the company with a total of 3.2 million shares.

In the latest ownership report on October 31st 2022, the top 20 fund holders increased their combined ownership of ALPN by 48 thousand shares. 4 funds bought 48,057 total additional shares and increased their ownership by an average of 8.80%. However 1 funds sold 248 total shares and decreased their ownership by an average of 0.46%.

Overall this is a positive sign as the number of shares owned by the top 20 mutual funds holding Alpine Immune Sciences increased by a net total of 47,809 in the latest report.

Mutual Funds Chart

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Latest Mutual Fund Ownership Changes

OwnerPercent OwnedPercent ChangeShares OwnedShare ChangeDate Reported
Vanguard Total Stock Mkt Idx Inv1.855%0.000%851,82902022-10-31
iShares Russell 2000 ETF0.702%0.325%322,4821,0452022-10-31
iShares Biotechnology ETF0.420%30.669%192,97545,2932022-10-31
Vanguard Extended Market Index Investor0.370%0.000%169,91102022-10-31
iShares Russell 2000 Value ETF0.188%0.296%86,4682552022-10-31
State St Russell Sm/Mid Cp® Indx NL Cl C0.173%0.000%79,20002022-10-31
State St Russell Sm Cap® Indx NL Cl C0.118%0.000%54,04102022-10-31
iShares Russell 2000 Growth ETF0.116%-0.464%53,202-2482022-10-31
Vanguard Russell 2000 ETF0.085%3.899%39,0091,4642022-10-31
Schwab Small Cap Index0.075%0.000%34,32302022-10-31
iShares Micro-Cap ETF0.070%0.000%32,07902022-10-31

Top Mutual Funds

OwnerPercent OwnedPercent ChangeShares OwnedShare ChangeDate Reported
Vanguard Total Stock Mkt Idx Inv1.855%0.000%851,82902022-10-31
Vanguard Instl Ttl Stck Mkt Idx Tr1.855%127.501%851,829477,4002022-09-30
iShares Russell 2000 ETF0.702%0.325%322,4821,0452022-10-31
iShares Biotechnology ETF0.420%30.669%192,97545,2932022-10-31
Vanguard Extended Market Index Investor0.370%0.000%169,91102022-10-31
Fidelity® Small Cap Index0.255%0.000%117,25402022-08-31
iShares Russell 2000 Value ETF0.188%0.296%86,4682552022-10-31
State St Russell Sm/Mid Cp® Indx NL Cl C0.173%0.000%79,20002022-10-31
Bridgeway Ultra-Small Company Market0.148%-26.937%67,811-25,0002022-09-30
Fidelity® Extended Market Index0.139%0.000%63,90902022-09-30
State St Russell Sm Cap® Indx NL Cl C0.118%0.000%54,04102022-10-31
iShares Russell 2000 Growth ETF0.116%-0.464%53,202-2482022-10-31
NT R2000 Index Fund - NL0.096%-0.456%43,890-2012022-09-30
Vanguard Russell 2000 ETF0.085%3.899%39,0091,4642022-10-31
Schwab Small Cap Index0.075%0.000%34,32302022-10-31
NT R2000 Index Fund - DC - NL - 20.071%0.421%32,7051372022-09-30
iShares Micro-Cap ETF0.070%0.000%32,07902022-10-31
BlackRock Extended Mkt Composite0.059%0.000%27,22427,2242022-06-30
NT R2000 Value Index Fund - NL0.058%-0.752%26,402-2002022-09-30
BlackRock Extended Equity Market K0.052%-0.911%24,037-2212022-09-30

Discussions

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dandanaiwo

$ALPN I blocked some bears and I liked it!

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145zip

$ALPN see you on the moon

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